Instable osmoreceptors and deficient thirst in hypothalamic hypopituitarism
نویسندگان
چکیده
منابع مشابه
Symptomatic hypothalamic hypopituitarism following radiotherapy.
Introduction The availability of hypothalamic-releasing hormones together with reliable assays of pituitary hormones in plasma have provided the means of accurate assessment of hypothalamic-pituitary function. A case is described of clinical hypopituitarism following radiotherapy to the head and neck, in which the use of these pituitary function tests has demonstrated damage at the hypothalamic...
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A 67-year-old man took labetalol (Trandate) 400 mg thrice daily and clonidine 0 3 mg daily from June 1977 for hypertension. Methyldopa had been withdrawn because of diarrhoea, and propranolol and clonidine had proved ineffective. Twelve weeks after beginning labetalol he developed an itchy eruption on his penis, which spread to the trunk and limbs. When he attended hospital 10 weeks later the e...
متن کاملPreoptic-hypothalamic periventricular lesions: thirst deficits and hypernatremia.
To assess the significance of stimulation studies suggesting an anteroventral third ventricle (AV3V) dipsogenic site of action for hyperosmotic and angiotensin thirst stimuli, electrolytic lesions of periventricular tissue surrounding AV3V were produced under ether anesthesia in rats preselected for responsiveness to subcutaneous angiotensin and hypertonic NaCl thirst challenges. Lesions limite...
متن کاملA case of hypothalamic hypopituitarism accompanied by recurrent severe hypoglycemia
INTRODUCTION Hypothalamic hypopituitarism is relatively rare cause of secondary adrenal deficiency which is often accompanied by severe hypoglycemia. Hydrocortisone replacement therapy is essential for this condition, but gastrointestinal symptom such as nausea and vomiting is not well-recognized adverse effect of hydrocortisone. CASE DESCRIPTION A 64-year-old-woman was referred to our hospit...
متن کاملPyrexia of unknown origin. Presenting sign of hypothalamic hypopituitarism.
A 62-year-old man was admitted to hospital 10 times over 12 years because of pyrexia of unknown origin. Hypothalamic hypopituitarism was diagnosed by dynamic tests including clomiphene, LRH, TRH and chlorpromazine stimulation. Lack of ACTH was demonstrated by long and short tetracosactrin tests. The aetiology of the disorder was believed to be previous encephalitis. Following substitution thera...
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ژورنال
عنوان ژورنال: Pediatric Research
سال: 1981
ISSN: 0031-3998,1530-0447
DOI: 10.1203/00006450-198101000-00063